Signature-Tagged Transposon Mutagenesis Identifies Novel Mycobacterium tuberculosis Genes Involved in the Parasitism of Human Macrophages

Using signature-tagged transposon mutagenesis, we isolated 23 Mycobacterium tuberculosis mutants, corresponding to 21 genes or genetic regions, attenuated in their ability to parasitize human macrophages. Mutants disrupted in the ABC transporter-encoding genes Rv0986 and Rv0987 were further characte...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Rosas-Magallanes, Vania, Stadthagen-Gomez, Gustavo, Rauzier, Jean, Barreiro, Luis B., Tailleux, Ludovic, Boudou, Frédéric, Griffin, Ruth, Nigou, Jérome, Jackson, Mary, Gicquel, Brigitte, Neyrolles, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828433/
https://ncbi.nlm.nih.gov/pubmed/17030567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00058-06
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge