Proteolytic Processing of the Cryptosporidium Glycoprotein gp40/15 by Human Furin and by a Parasite-Derived Furin-Like Protease Activity

The apicomplexan parasite Cryptosporidium causes diarrheal disease worldwide. Proteolytic processing of proteins plays a significant role in host cell invasion by apicomplexan parasites. In previous studies, we described gp40/15, a Cryptosporidium sp. glycoprotein that is proteolytically cleaved to...

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Главные авторы: Wanyiri, Jane W., O'Connor, Roberta, Allison, Geneve, Kim, Kami, Kane, Anne, Qiu, Jiazhou, Plaut, Andrew G., Ward, Honorine D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2007
Предметы:
Fungal and Parasitic Infections
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828422/
https://ncbi.nlm.nih.gov/pubmed/17043102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00944-06
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