A Bile Salt Hydrolase of Brucella abortus Contributes to the Establishment of a Successful Infection through the Oral Route in Mice

Choloylglycine hydrolase (CGH), a bile salt hydrolase, has been annotated in all the available genomes of Brucella species. We obtained the Brucella CGH in recombinant form and demonstrated in vitro its capacity to cleave glycocholate into glycine and cholate. Brucella abortus 2308 (wild type) and i...

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Autores principales: Delpino, M. Victoria, Marchesini, María I., Estein, Silvia M., Comerci, Diego J., Cassataro, Juliana, Fossati, Carlos A., Baldi, Pablo C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
Materias:
Molecular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828384/
https://ncbi.nlm.nih.gov/pubmed/17088355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00952-06
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