Stevioside Counteracts Beta-Cell Lipotoxicity without Affecting Acetyl CoA Carboxylase

Chronic exposure to high levels of free fatty acids impairs beta-cell function (lipotoxicity). Then basal insulin secretion (BIS) is increased and glucose-stimulated insulin secretion (GSIS) is inhibited. Acetyl CoA carboxylase (ACC) acts as the sensor for insulin secretion in pancreatic beta-cells...

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Detalhes bibliográficos
Main Authors: Chen, Jianguo, Jeppesen, Per Bendix, Nordentoft, Iver, Hermansen, Kjeld
Formato: Artigo
Idioma:Inglês
Publicado em: SBDR - Society for Biomedical Diabetes Research 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828288/
https://ncbi.nlm.nih.gov/pubmed/17487342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2006.3.178
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