Variable RXR requirements for thyroid hormone responsiveness of endogenous genes

Thyroid hormone receptors heterodimerize with retinoid X receptors in vitro and it is widely assumed that these heterodimers mediate the T3 induction of target genes. However, the importance of RXR for the T3 induction of endogenous genes has not been assessed. We used cDNA microarrays to identify 5...

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Main Authors: Diallo, Ericka M., Wilhelm, Kenneth G., Thompson, Deborah L., Koenig, Ronald J.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828278/
https://ncbi.nlm.nih.gov/pubmed/17161906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2006.11.004
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