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Upregulation of Substance P in Low-Threshold Myelinated Afferents Is Not Required for Tactile Allodynia in the Chronic Constriction Injury and Spinal Nerve Ligation Models

It has been proposed that substance P and calcitonin gene-related peptide (CGRP) are upregulated in low-threshold myelinated primary afferents after certain types of nerve injury, and that release of substance P from these afferents contributes to the resulting tactile allodynia. To test this hypoth...

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Détails bibliographiques
Auteurs principaux: Hughes, David I., Scott, Dugald T., Riddell, John S., Todd, Andrew J.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828212/
https://ncbi.nlm.nih.gov/pubmed/17314299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5401-06.2007
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