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Modeling How CD46 Deficiency Predisposes to Atypical Hemolytic Uremic Syndrome

Mutations in complement regulatory proteins predispose to the development of aHUS. Approximately 50% of patients bear a mutation in one of three complement control proteins, factor H, factor I, or membrane cofactor protein (MCP; CD46). Another membrane regulator that is closely related to MCP, decay...

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Main Authors: Liszewski, M. Kathryn, Leung, Marilyn K., Schraml, Barbara, Goodship, Timothy H.J., Atkinson, John P.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828070/
https://ncbi.nlm.nih.gov/pubmed/17027083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2006.08.024
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