Signature Gene Expression Profiles Discriminate between Isoniazid-, Thiolactomycin-, and Triclosan-Treated Mycobacterium tuberculosis

Genomic technologies have the potential to greatly increase the efficiency of the drug development process. As part of our tuberculosis drug discovery program, we used DNA microarray technology to profile drug-induced effects in Mycobacterium tuberculosis. Expression profiles of M. tuberculosis trea...

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Detalhes bibliográficos
Main Authors: Betts, Joanna C., McLaren, Alistair, Lennon, Mark G., Kelly, Fiona M., Lukey, Pauline T., Blakemore, Steve J., Duncan, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC182614/
https://ncbi.nlm.nih.gov/pubmed/12936993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.9.2903-2913.2003
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