Effects of 16S rRNA Gene Mutations on Tetracycline Resistance in Helicobacter pylori

The triple-base-pair 16S rDNA mutation AGA(926-928)→TTC mediates high-level tetracycline resistance in Helicobacter pylori. In contrast, single- and double-base-pair mutations mediated only low-level tetracycline resistance and decreased growth rates in the presence of tetracycline, explaining the p...

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Autors principals: Gerrits, Monique M., Berning, Marco, Van Vliet, Arnoud H. M., Kuipers, Ernst J., Kusters, Johannes G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC182601/
https://ncbi.nlm.nih.gov/pubmed/12937008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.9.2984-2986.2003
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