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Fully Differentiated HIV-1 Specific CD8+ T Effector Cells Are More Frequently Detectable in Controlled than in Progressive HIV-1 Infection

BACKGROUND: CD8+ T cells impact control of viral infections by direct elimination of infected cells and secretion of a number of soluble factors. In HIV-1 infection, persistent HIV-1 specific IFN-γ+ CD8+ T cell responses are detected in the setting of disease progression, consistent with functional...

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Main Authors: Addo, Marylyn M., Draenert, Rika, Rathod, Almas, Verrill, Cori L., Davis, Benjamin T., Gandhi, Rajesh T., Robbins, Gregory K., Basgoz, Nesli O., Stone, David R., Cohen, Daniel E., Johnston, Mary N., Flynn, Theresa, Wurcel, Alysse G., Rosenberg, Eric S., Altfeld, Marcus, Walker, Bruce D.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1824710/
https://ncbi.nlm.nih.gov/pubmed/17389912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000321
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