Fully Differentiated HIV-1 Specific CD8+ T Effector Cells Are More Frequently Detectable in Controlled than in Progressive HIV-1 Infection

BACKGROUND: CD8+ T cells impact control of viral infections by direct elimination of infected cells and secretion of a number of soluble factors. In HIV-1 infection, persistent HIV-1 specific IFN-γ+ CD8+ T cell responses are detected in the setting of disease progression, consistent with functional...

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Detalhes bibliográficos
Main Authors: Addo, Marylyn M., Draenert, Rika, Rathod, Almas, Verrill, Cori L., Davis, Benjamin T., Gandhi, Rajesh T., Robbins, Gregory K., Basgoz, Nesli O., Stone, David R., Cohen, Daniel E., Johnston, Mary N., Flynn, Theresa, Wurcel, Alysse G., Rosenberg, Eric S., Altfeld, Marcus, Walker, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1824710/
https://ncbi.nlm.nih.gov/pubmed/17389912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000321
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