Anthrax Toxin Receptor 2 Determinants that Dictate the pH Threshold of Toxin Pore Formation

The anthrax toxin receptors, ANTXR1 and ANTXR2, act as molecular clamps to prevent the protective antigen (PA) toxin subunit from forming pores until exposure to low pH. PA forms pores at pH ∼6.0 or below when it is bound to ANTXR1, but only at pH ∼5.0 or below when it is bound to ANTXR2. Here, stru...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Scobie, Heather M., Marlett, John M., Rainey, G. Jonah A., Lacy, D. Borden, Collier, R. John, Young, John A.T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2007
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1824706/
https://ncbi.nlm.nih.gov/pubmed/17389920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000329
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