Construction of a Biotin-Overproducing Strain of Serratia marcescens

We have isolated mutants resistant to acidomycin, a biotin analog, from Serratia marcescens Sr41. Strain SB304, resistant to 0.5 mg of acidomycin (frequently called actithiazic acid) per ml, produced 5 mg of d-biotin per liter of a medium containing sucrose and urea. Strain SB412, which was isolated...

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Détails bibliographiques

Publié dans:	Appl Environ Microbiol
Auteurs principaux:	Sakurai, Naoki, Imai, Yuji, Masuda, Makoto, Komatsubara, Saburo, Tosa, Tetsuya
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1993
Sujets:	Physiology and Biotechnology
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182377/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16349036/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.59.9.2857-2863.1993
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