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Genetic evidence that the bacteriophage φX174 lysis protein inhibits cell wall synthesis

Protein E, a 91-residue membrane protein of φX174, causes lysis of the host in a growth-dependent manner reminiscent of cell wall antibiotics, suggesting E acts by inhibiting peptidoglycan synthesis. In a search for the cellular target of E, we previously have isolated recessive mutations in the hos...

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Autors principals: Bernhardt, Thomas G., Roof, William D., Young, Ry
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC18234/
https://ncbi.nlm.nih.gov/pubmed/10760296
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