A role for surface lymphotoxin in experimental autoimmune encephalomyelitis independent of LIGHT

In studies using genetically deficient mice, a role for the lymphotoxin (LT) system in the pathogenesis of experimental autoimmune encephalomyelitis (EAE) has remained controversial. Here, we have reassessed this conclusion by using a fusion protein decoy that blocks the LT pathway in vivo without e...

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Main Authors: Gommerman, Jennifer L., Giza, Keith, Perper, Stuart, Sizing, Irene, Ngam-ek, Apinya, Nickerson-Nutter, Cheryl, Browning, Jeffrey L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2003
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC182210/
https://ncbi.nlm.nih.gov/pubmed/12952924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318648
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