Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells

IL-12 p40–related cytokines such as IL-12 p35/p40 heterodimer and IL-23 (p19/p40) are potent regulators of adaptive immune responses. Little is known, however, about the transcriptional regulation of the p40 gene in vivo. In an attempt toward this goal, we have generated transgenic mice expressing f...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Becker, Christoph, Wirtz, Stefan, Blessing, Manfred, Pirhonen, Jaana, Strand, Dennis, Bechthold, Oliver, Frick, Julia, Galle, Peter R., Autenrieth, Ingo, Neurath, Markus F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC182190/
https://ncbi.nlm.nih.gov/pubmed/12952918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317464
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados