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Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells

Systemic tolerance can be induced by the introduction of antigen into an immune-privileged site. Here we investigated the role of complement in the induction of tolerance after intraocular injection. We found that the development of antigen-specific tolerance is dependent on a complement activation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sohn, Jeong-Hyeon, Bora, Puran S., Suk, Hye-Jung, Molina, Hector, Kaplan, Henry J., Bora, Nalini S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1821085/
https://ncbi.nlm.nih.gov/pubmed/12514742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm814
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