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A novel checkpoint mechanism regulating the G1/S transition

Ultraviolet irradiation of fission yeast cells in G1 phase induced a delay in chromatin binding of replication initiation factors and, consistently, a transient delay in S-phase entry. The cell cycle delay was totally dependent on the Gcn2 kinase, a sensor of the nutritional status, and was accompan...

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Detalhes bibliográficos
Main Authors: Tvegård, Tonje, Soltani, Héla, Skjølberg, Henriette C., Krohn, Marit, Nilssen, Esben A., Kearsey, Stephen E., Grallert, Beáta, Boye, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820939/
https://ncbi.nlm.nih.gov/pubmed/17369398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.421807
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