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Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method

Chromatin remodeling complexes (remodelers) are large, multisubunit macromolecular assemblies that use ATP hydrolysis to alter the structure and positioning of nucleosomes. The mechanisms proposed for remodeler action on nucleosomes are diverse, and require structural evaluation and insights. Previo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Leschziner, Andres E., Saha, Anjanabha, Wittmeyer, Jacqueline, Zhang, Yongli, Bustamante, Carlos, Cairns, Bradley R., Nogales, Eva
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820885/
https://ncbi.nlm.nih.gov/pubmed/17360331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700706104
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