p90 RSK-1 associates with and inhibits neuronal nitric oxide synthase

Evidence is presented that RSK1 (ribosomal S6 kinase 1), a downstream target of MAPK (mitogen-activated protein kinase), directly phosphorylates nNOS (neuronal nitric oxide synthase) on Ser(847) in response to mitogens. The phosphorylation thus increases greatly following EGF (epidermal growth facto...

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Detalhes bibliográficos
Main Authors: Song, Tao, Sugimoto, Katsuyoshi, Ihara, Hideshi, Mizutani, Akihiro, Hatano, Naoya, Kume, Kodai, Kambe, Toshie, Yamaguchi, Fuminori, Tokuda, Masaaki, Watanabe, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820814/
https://ncbi.nlm.nih.gov/pubmed/16984226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060580
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