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Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

Field cancerization predisposes the upper aerodigestive tract mucosa to the formation of multiple primary tumors, when exposed to environmental carcinogens. Up-regulation of epidermal growth factor receptor occurs early in squamous cell carcinogenesis and is critical for the loss of growth control i...

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Bibliografische gegevens
Hoofdauteurs: Grandis, Jennifer Rubin, Drenning, Stephanie D., Zeng, Qing, Watkins, Simon C., Melhem, Mona F., Endo, Sohei, Johnson, Daniel E., Huang, Leaf, He, Yukai, Kim, Jae D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18206/
https://ncbi.nlm.nih.gov/pubmed/10760290
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