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Increased hepatic telomerase activity in a rat model of iron overload: a role for altered thiol redox state?

Telomeres are repeated sequences at chromosome ends that are incompletely replicated during mitosis. Telomere shortening caused by proliferation or oxidative damage culminates in replicative arrest and senescence, which may impair regeneration during chronic liver injury. While the effects of experi...

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Detalhes bibliográficos
Main Authors: Brown, Kyle E., Mathahs, M. Meleah, Broadhurst, Kimberly A., Coleman, Mitchell C., Ridnour, Lisa A., Schmidt, Warren N., Spitz, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820590/
https://ncbi.nlm.nih.gov/pubmed/17189828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2006.10.039
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