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Dimerization of Protein Tyrosine Phosphatase σ Governs both Ligand Binding and Isoform Specificity

Signaling through receptor protein tyrosine phosphatases (RPTPs) can influence diverse processes, including axon development, lymphocyte activation, and cell motility. The molecular regulation of these enzymes, however, is still poorly understood. In particular, it is not known if, or how, the dimer...

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Detalhes bibliográficos
Main Authors: Lee, Simon, Faux, Clare, Nixon, Jennifer, Alete, Daniel, Chilton, John, Hawadle, Muhamed, Stoker, Andrew W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820468/
https://ncbi.nlm.nih.gov/pubmed/17178832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00535-06
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