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Dimerization of Protein Tyrosine Phosphatase σ Governs both Ligand Binding and Isoform Specificity

Signaling through receptor protein tyrosine phosphatases (RPTPs) can influence diverse processes, including axon development, lymphocyte activation, and cell motility. The molecular regulation of these enzymes, however, is still poorly understood. In particular, it is not known if, or how, the dimer...

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Détails bibliographiques
Auteurs principaux: Lee, Simon, Faux, Clare, Nixon, Jennifer, Alete, Daniel, Chilton, John, Hawadle, Muhamed, Stoker, Andrew W.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820468/
https://ncbi.nlm.nih.gov/pubmed/17178832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00535-06
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