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Role of Cytochrome c in Apoptosis: Increased Sensitivity to Tumor Necrosis Factor Alpha Is Associated with Respiratory Defects but Not with Lack of Cytochrome c Release

Although the role of cytochrome c in apoptosis is well established, details of its participation in signaling pathways in vivo are not completely understood. The knockout for the somatic isoform of cytochrome c caused embryonic lethality in mice, but derived embryonic fibroblasts were shown to be re...

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Autori principali: Vempati, Uma D., Diaz, Francisca, Barrientos, Antoni, Narisawa, Sonoko, Mian, Abdul M., Millán, José Luis, Boise, Lawrence H., Moraes, Carlos T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820455/
https://ncbi.nlm.nih.gov/pubmed/17210651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00287-06
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