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Fission Yeast Cut8 Is Required for the Repair of DNA Double-Strand Breaks, Ribosomal DNA Maintenance, and Cell Survival in the Absence of Rqh1 Helicase

Schizosaccharomyces pombe Rqh1 is a member of the RecQ DNA helicase family. Members of this protein family are mutated in cancer predisposition diseases, causing Bloom's, Werner, and Rothmund-Thomson syndromes. Rqh1 forms a complex with topoisomerase III and is proposed to process or disrupt ab...

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Hlavní autoři: Kearsey, Stephen E., Stevenson, Abigail L., Toda, Takashi, Wang, Shao-Win
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820446/
https://ncbi.nlm.nih.gov/pubmed/17178839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01495-06
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