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Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes.

In mutant Escherichia coli with temperature-sensitive peptidyl-tRNA hydrolase (aminoacyl-tRNA hydrolase; EC 3.1.1.29), peptidyl-tRNA accumulates at the nonpermissive temperature (40 degrees C), and the cells die. These consequences of high temperature were enhanced if the cells were first treated wi...

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Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Antimicrob Agents Chemother
Príomhchruthaitheoirí: Menninger, J R, Otto, D P
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 1982
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182017/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6179465/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.5.811
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