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Development of clinical resistance to acyclovir in herpes simplex virus-infected mice receiving oral therapy.

Mice inoculated in the ear pinna with herpes simplex virus were treated effectively by including 1 mg of acyclovir per ml in the drinking water. During a 5-day course of treatment the development of resistance was not readily apparent. However, when a suboptimal therapeutic dose was used and virus w...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Antimicrob Agents Chemother
المؤلف الرئيسي: Field, H J
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology (ASM) 1982
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182005/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7103454/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.5.744
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