Human cytolytic and interferon γ-secreting CD8(+) T lymphocytes specific for Mycobacterium tuberculosis

Protective immunity to Mycobacterium tuberculosis is poorly understood, but mounting evidence, at least in animal models, implicates major histocompatibility complex class I-restricted CD8(+) T cells as an essential component. By using a highly sensitive assay for single cell interferon γ release, w...

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Bibliographic Details
Main Authors: Lalvani, Ajit, Brookes, Roger, Wilkinson, Robert J., Malin, Adam S., Pathan, Ansar A., Andersen, Peter, Dockrell, Hazel, Pasvol, Geoffrey, Hill, Adrian V. S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC18198/
https://ncbi.nlm.nih.gov/pubmed/9419365
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