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Life span and stress resistance of Caenorhabditis elegans are differentially affected by glutathione transferases metabolizing 4-hydroxynon-2-enal

The lipid peroxidation product 4-hydroxynon-2-enal (4-HNE) forms as a consequence of oxidative stress, and acts as a signaling molecule or, at superphysiological levels, as a toxicant. The steady-state concentration of the compound reflects the balance between its generation and its metabolism, prim...

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Detalhes bibliográficos
Main Authors: Ayyadevara, Srinivas, Dandapat, Abhijit, Singh, Sharda P., Siegel, Eric R., Shmookler Reis, Robert J., Zimniak, Ludwika, Zimniak, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1819584/
https://ncbi.nlm.nih.gov/pubmed/17157356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2006.11.025
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