Cardiac and vascular K(ATP) channels in rats are activated by endogenous epoxyeicosatrienoic acids through different mechanisms

We have reported that epoxyeicosatrienoic acids (EETs), the cytochrome P450 (CYP) epoxygenase metabolites of arachidonic acid (AA), are potent sarcolemmal ATP-sensitive K(+) (K(ATP)) channel activators. However, activation of cardiac and vascular K(ATP) channels by endogenously produced EETs under p...

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Detalhes bibliográficos
Main Authors: Lu, Tong, Ye, Dan, Wang, Xiaoli, Seubert, John M, Graves, Joan P, Bradbury, J Alyce, Zeldin, Darryl C, Lee, Hon-Chi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1819457/
https://ncbi.nlm.nih.gov/pubmed/16793897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.113985
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