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The antimalarial drug mefloquine binds to membrane phospholipids.

The new antimalarial drug mefloquine bound with high affinity (Kd approximately 3 X 10-7 M) to membrane lipids of normal mouse erythrocytes and of erythrocytes infected either with chloroquine-susceptible or chloroquine-resistant Plasmodium berghei. Approximately 80 nmol of mefloquine was bound per...

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Bibliografske podrobnosti
Main Authors: Chevli, R, Fitch, C D
Format: Artigo
Jezik:Inglês
Izdano: 1982
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC181945/
https://ncbi.nlm.nih.gov/pubmed/6979309
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