Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys

The potential utility of plasmid DNA as an HIV-1 vaccination modality currently is an area of active investigation. However, recent studies have raised doubts as to whether plasmid DNA alone will elicit immune responses of sufficient magnitude to protect against pathogenic AIDS virus challenges. We...

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Autori principali: Barouch, Dan H., Craiu, Abie, Kuroda, Marcelo J., Schmitz, Jörn E., Zheng, Xin Xiao, Santra, Sampa, Frost, Julie D., Krivulka, Georgia R., Lifton, Michelle A., Crabbs, Carroll L., Heidecker, Gwendolyn, Perry, Helen C., Davies, Mary-Ellen, Xie, Hong, Nickerson, Christine E., Steenbeke, Tavis D., Lord, Carol I., Montefiori, David C., Strom, Terry B., Shiver, John W., Lewis, Mark G., Letvin, Norman L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2000
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC18194/
https://ncbi.nlm.nih.gov/pubmed/10759543
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