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Inhibition of rotaviruses by selected antiviral substances: mechanisms of viral inhibition and in vivo activity.

Several RNA virus inhibitors were evaluated against simian (SA11) rotavirus infections in vitro and murine rotavirus gastroenteritis in vivo. Test compounds included 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin), 3-deazaguanine (3-DG), 3-deazauridine, and 9-(S)-(2,3-dihydroxypropyl...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Smee, D F, Sidwell, R W, Clark, S M, Barnett, B B, Spendlove, R S
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1982
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181831/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6282209/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.1.66
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