Activity of Di-β-Lysyl-Capreomycin IIA and Palmitoyl Tuberactinamine N Against Drug-Resistant Mutants with Altered Ribosomes

The effects of 61 synthetic tuberactinomycin derivatives on polypeptide synthesis were tested in bacterial cell-free systems. Di-β-lys-capreomycin IIA was more effective than the natural product. Palmitoyl tuberactinamine N inhibited the growth of tuberactinomycin-resistant mutants and was not a rib...

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הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Yamada, Takeshi, Teshima, Tadashi, Shiba, Tetsuo
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 1981
נושאים:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181807/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6173016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.20.6.834
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