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Evaluation of carbodine, the carbocyclic analog of cytidine, and related carbocyclic analogs of pyrimidine nucleosides for antiviral activity against human influenza Type A viruses.

Carbodine, the carbocyclic analog of cytidine, was found to possess significant antiviral activity against influenza virus types A0/PR-8/34 and A2/Aichi/2/68 (Hong Kong) in vitro. The compound selectively inhibited PR-8 influenza virus-induced cytopathogenic effects in Madin-Darby canine kidney and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shannon, W M, Arnett, G, Westbrook, L, Shealy, Y F, O'Dell, C A, Brockman, R W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1981
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC181796/
https://ncbi.nlm.nih.gov/pubmed/7325642
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