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Activation of the cGMP/PKG pathway inhibits electrical activity in rabbit urethral interstitial cells of Cajal by reducing the spatial spread of Ca(2+) waves

In the present study we used a combination of patch clamping and fast confocal Ca(2+) imaging to examine the effects of activators of the nitric oxide (NO)/cGMP pathway on pacemaker activity in freshly dispersed ICC from the rabbit urethra, using the amphotericin B perforated patch configuration of...

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Autors principals: Sergeant, G P, Johnston, Louise, McHale, N G, Thornbury, K D, Hollywood, M A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817801/
https://ncbi.nlm.nih.gov/pubmed/16644801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.108621
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