Essential role of the persistent sodium current in spike initiation during slowly rising inputs in mouse spinal neurones

Spinal motoneurons, like many neurons, respond with repetitive spiking to sustained inputs. The afterhyperpolarization (AHP) that follows each spike, however, decays relatively slowly in motoneurons. The slow depolarization during this decay should allow sodium (Na(+)) channel inactivation to keep u...

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Bibliografiska uppgifter
Huvudupphovsmän: Kuo, J J, Lee, R H, Zhang, L, Heckman, C J
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2006
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817738/
https://ncbi.nlm.nih.gov/pubmed/16728453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.107094
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