Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38α in abrogating myoblast proliferation

The p38 mitogen-activated protein kinase (MAPK) pathway plays a critical role in skeletal muscle differentiation. However, the relative contribution of the four p38 MAPKs (p38α, p38β, p38γ and p38δ) to this process is unknown. Here we show that myoblasts lacking p38α, but not those lacking p38β or p...

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Detalhes bibliográficos
Main Authors: Perdiguero, Eusebio, Ruiz-Bonilla, Vanessa, Gresh, Lionel, Hui, Lijian, Ballestar, Esteban, Sousa-Victor, Pedro, Baeza-Raja, Bernat, Jardí, Mercè, Bosch-Comas, Anna, Esteller, Manel, Caelles, Carme, Serrano, Antonio L, Wagner, Erwin F, Muñoz-Cánoves, Pura
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817635/
https://ncbi.nlm.nih.gov/pubmed/17304211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601587
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