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Replication foci dynamics: replication patterns are modulated by S-phase checkpoint kinases in fission yeast

Although the molecular enzymology of DNA replication is well characterised, how and why it occurs in discrete nuclear foci is unclear. Using fission yeast, we show that replication takes place in a limited number of replication foci, whose distribution changes with progression through S phase. These...

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Bibliografiske detaljer
Main Authors: Meister, Peter, Taddei, Angela, Ponti, Aaron, Baldacci, Giuseppe, Gasser, Susan M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1817620/
https://ncbi.nlm.nih.gov/pubmed/17304223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601538
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