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Mutagenicity of quindoxin, its metabolites, and two substituted quinoxaline-di-N-oxides.

The quinoxaline-di-N-oxides carbadox, olaquindox, and quindoxin, which are potent antibacterial agents, were tested for mutagenicity in the Salmonella microsomal system. They all induced base pair substitutions and frameshift mutations in Salmonella, and occurred independently of the presence of a r...

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Detalhes bibliográficos
Main Authors: Beutin, L, Preller, E, Kowalski, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC181697/
https://ncbi.nlm.nih.gov/pubmed/7030199
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