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Trimethoprim-sulfamethoxazole therapy of experimental Escherichia coli meningitis in rabbits.

We used two strains of ampicillin-susceptible Escherichia coli to produce meningitis in rabbits and utilized these models (i) to compare the killing effects of parenteral trimethoprim-sulfamethoxazole (TMP-SMZ) and ampicillin on E. coli in cerebrospinal fluid after 8 h of treatment and (ii) to measu...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Mylotte, J M, Bates, T R, Sergeant, K A, Matson, R E, Beam, T R
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1981
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181637/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7025751/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.20.1.81
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