Hexamethylene bisacetamide induces programmed cell death (apoptosis) and down-regulates BCL-2 expression in human myeloma cells

Multiple myeloma (MM) is a B cell malignancy characterized by the expansion of monoclonal Ig-secreting plasma cells with low proliferative activity. It is postulated that inhibition of physiologic cell death is an underlying factor in the pathophysiology of MM. The development of chemoresistance is...

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Detalhes bibliográficos
Main Authors: Siegel, D. S., Zhang, X., Feinman, R., Teitz, T., Zelenetz, A., Richon, V. M., Rifkind, R. A., Marks, P. A., Michaeli, J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18160/
https://ncbi.nlm.nih.gov/pubmed/9419346
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