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The Role of Subunit Assembly in Peripherin-2 Targeting to Rod Photoreceptor Disk Membranes and Retinitis Pigmentosa

Peripherin-2 is a member of the tetraspanin family of membrane proteins that plays a critical role in photoreceptor outer segment disk morphogenesis. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP). To ident...

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Main Authors: Loewen, Christopher J.R., Moritz, Orson L., Tam, Beatrice M., Papermaster, David S., Molday, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC181576/
https://ncbi.nlm.nih.gov/pubmed/12925772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-02-0077
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