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Cortactin Tyrosine Phosphorylation Requires Rac1 Activity and Association with the Cortical Actin Cytoskeleton

Cortactin is an F-actin binding protein that activates actin-related protein 2/3 complex and is localized within lamellipodia. Cortactin is a substrate for Src and other protein tyrosine kinases involved in cell motility, where its phosphorylation on tyrosines 421, 466, and 482 in the carboxy termin...

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Udgivet i:Mol Biol Cell
Principais autores: Head, Julie A., Jiang, Dongyan, Li, Min, Zorn, Lynda J., Schaefer, Erik M., Parsons, J. Thomas, Weed, Scott A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2003
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181562/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12925758/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-11-0753
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