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Hypoxia Regulates Assembly of Cilia in Suppressors of Tetrahymena Lacking an Intraflagellar Transport Subunit Gene

We cloned a Tetrahymena thermophila gene, IFT52, encoding a homolog of the Chlamydomonas intraflagellar transport protein, IFT52. Disruption of IFT52 led to loss of cilia and incomplete cytokinesis, a phenotype indistinguishable from that of mutants lacking kinesin-II, a known ciliary assembly trans...

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Publicat a:Mol Biol Cell
Autors principals: Brown, Jason M., Fine, Noah A., Pandiyan, Gautham, Thazhath, Rupal, Gaertig, Jacek
Format: Artigo
Idioma:Inglês
Publicat: American Society for Cell Biology 2003
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181560/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12925756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-03-0166
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