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Sphingoid base 1-phosphate phosphatase: A key regulator of sphingolipid metabolism and stress response

The sphingolipid metabolites ceramide and sphingosine-1-phosphate are second messengers with opposing roles in mammalian cell growth arrest and survival; their relative cellular level has been proposed to be a rheostat that determines the fate of cells. This report demonstrates that this rheostat is...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Mandala, Suzanne M., Thornton, Rosemary, Tu, Zhenxing, Kurtz, Myra B., Nickels, Joseph, Broach, James, Menzeleev, Ramil, Spiegel, Sarah
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18156/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9419344/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.1.150
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