Φορτώνει......
Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8(+) T cell functions during chronic viral infection
In persistent viral infections, the host's immune system is challenged by the constant exposure to antigen, potentially causing continuous activation of CD8(+) T cells with subsequent immunopathology. Here we demonstrate, for experimental chronic lymphocytic choriomeningitis virus and human HIV...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815473/ https://ncbi.nlm.nih.gov/pubmed/17360564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610335104 |
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