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Dose–Response Analysis of Locomotor Activity and Stereotypy in Dopamine D3 Receptor Mutant Mice Following Acute Amphetamine

Accumulating evidence suggests that dopamine D3 receptor (D3R) stimulation is inhibitory to spontaneous and psychostimulant-induced locomotion through opposition of concurrent D1R and D2R-mediated signaling. To evaluate this model, we used homozygous D3R mutant mice and wild-type controls to investi...

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Bibliographic Details
Main Authors: McNAMARA, ROBERT K., LOGUE, AARON, STANFORD, KEVIN, XU, MING, ZHANG, JIANHUA, RICHTAND, NEIL M.
Format: Artigo
Language:Inglês
Published: 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1815379/
https://ncbi.nlm.nih.gov/pubmed/16856172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20315
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