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Resistance to antibiotic synergism in Streptococcus faecalis: further studies with amikacin and with a new amikacin derivative, 4'-deoxy, 6'-N-methylamikacin.

Streptococcus faecalis strains may resist penicillin-aminoglycoside synergy by the production of plasmid-mediated aminoglycoside-modifying enzymes. One of these enzymes, aminoglycoside 3'-phosphotransferase, has been shown to have a broad range of substrate specificity, including amikacin. We have s...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Calderwood, S B, Wennersten, C, Moellering, R C
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1981
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181475/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6264851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.4.549
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