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Resistance to antibiotic synergism in Streptococcus faecalis: further studies with amikacin and with a new amikacin derivative, 4'-deoxy, 6'-N-methylamikacin.

Streptococcus faecalis strains may resist penicillin-aminoglycoside synergy by the production of plasmid-mediated aminoglycoside-modifying enzymes. One of these enzymes, aminoglycoside 3'-phosphotransferase, has been shown to have a broad range of substrate specificity, including amikacin. We h...

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Bibliographische Detailangaben
Hauptverfasser: Calderwood, S B, Wennersten, C, Moellering, R C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1981
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC181475/
https://ncbi.nlm.nih.gov/pubmed/6264851
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