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Pharmacokinetics of moxalactam in patients with renal insufficiency.

Moxalactam pharmacokinetics were determined in 18 patients with renal insufficiency (creatinine clearance, 0 to 99 ml/min). Each patient was given 0.5 g of moxalactam intramuscularly. Drug half-life ranged from 4.1 to 49.1 h and correlated inversely with creatinine clearance (r = -0.97). Total body...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Lam, M, Manion, C V, Czerwinski, A W
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1981
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181454/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6454383/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.3.461
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