Pharmacokinetics of cefuroxime in normal and impaired renal function: comparison of high-pressure liquid chromatography and microbiological assays.

The pharmacokinetics of cefuroxime were studied after a single dose of 750 mg was given intravenously to each of 21 male volunteers grouped according to their creatinine clearances; these clearances were 60 to 120, 20 to 59, and less than 20 ml/min per 1.73 m,2 respectively, for groups 1 (12 subject...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Bundtzen, R W, Toothaker, R D, Nielson, O S, Madsen, P O, Welling, P G, Craig, W A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1981
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181451/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7247369/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.19.3.443
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